ABSTRACT
Objective To study the protective effect of cerium on changes of MDA content and DNA damage induced by cadmium in loach liver.Methods The loaches were randomly divided into control group and low (0.025 mg/L),moderate(0.25 mg/L),high(2.5 mg/L)Cd~(2+) exposed group and low(0.025 mg/L Cd~(2+)+0.025 Ce~(3+)),moderate(0.25 mg/L Cd~(2+)+0.25 mg/L Ce~(3+)),high (2.5 mg/L Cd~(2+)+2.5 mg/L Ce~(3+))CdE~(2+)+Ce~(3+) exposed group,the MDA content in loach liver was determined at 1d,2d,3d,5d,7d and 10 d of exposure with the method of TBA,the MDA damage in loach liver was detected at 7 d with the method of agarose gel electrophoresis.Results The MDA content of low Cd~(2+) exposed group was higher than that in the control at ld and 2 d (P
ABSTRACT
Glutaraldehyde, as a sterilizing agent, is a broad spectrum, reliable effect, low toxicity, thrill and causticity with longer period of validity, so it is widely used in the hospitals. But in clinic application there were increasing evidences that glutaraldehyde has toxicity to human body. It can solidify the tissue, mucous membrane and skin, also affect the healing up of the wound. Physiological property of glutaraldehyde was briefly introduced in this paper and the features in application of glutaraldehyde and the merit and potential toxicity to human body were also presented in details.